King's College London

Postdoctoral Research Associate

Reference: THW/17/059639/000979
Salary Details: Grade 6: £32,958 per annum
Allowances: £2,923 London Living Allowance
Contract Type: Temporary/Fixed term
Contract Term: Full time

We are seeking a highly motivated and talented postdoctoral researcher for a 1 year fixed-term contract, starting 1 October 2017, to develop nanomaterial-based gene delivery strategies for the topical treatment of genetic skin conditions. We are looking for someone with experience in gene/drug delivery using nanovectors. Further experience with optical microscopy and cell biology would be advantageous.

THE GROUP
The Nanomaterials and Biointerfaces group of Dr. Chiappini is based in the Centre for Craniofacial and Regenerative Biology at King’s College London. The group blends nanotechnology, bioengineering and cell biology to develop advanced materials for dynamic intracellular interaction. We leverage this controlled cell interaction to engineer platforms for regenerative medicine and precision medicine. This project is in collaboration with the groups of Professor John McGrath and Professor Maddy Parsons. For more information visit http://chiappinilab.com.

THE PROJECT
This exciting project is to investigate nanomaterial based strategies for the local targeted delivery of DNA plasmid to skin blisters due to genetic skin disease. The aims of the project are to identify an efficient delivery strategy to skin organoid cultures and to excised clinical samples, and validate the correction of the genetic defect, alongside its effects promoting wound healing. The work follows up from two of our recent publications on nanodelivery strategies for DNA plasmids (Chiappini et al. Nature Materials 2015) and gene-therapy correction of skin diseases (Georgiadis et al. Journal of Investigative Dermatology 2016).

The selection process will include competency based questions, a presentation, an assessment and a panel interview.

Informal discussion to find out more about the role are strongly encouraged. Please contact Dr. Ciro Chiappini ciro.chiappini@kcl.ac.uk.

To apply for this role, please go to the King’s College London HireWire Job Board and register to download and submit the specified application form.

Closing date: 13 August 2017

Attachments:
Job Pack | (Word Document 273k)

If you have questions about this role, please contact: Dr Ciro Chiappini, Email: ciro.chiappini@kcl.ac.uk,

Application form:


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